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Protein kinase C (PKC) is an important and differentially distributed serine/threonine kinase involved in the transduction of signals from the membrane to the nucleus and in other cellular pathways. In the present study, we have investigated the relationship between the expression levels of six PKC isoforms (betaI, betaII, gamma, delta, epsilon, and zeta) in breast cancers to clinicopathological features and survival. The expression of all six PKC isoforms was detected by immunoblot and visualized by chemiluminescence. Immunohistochemistry with PKC isoform-specific antibodies was used to assess the degree of staining. A total of 167 formalin-fixed paraffin-embedded breast tumor samples were analyzed using the anti-PKC betaI antibody. The average staining scores in the cases ranged from 0 (no staining) to 4 (intense staining). When the 67 cases that also stained positively with estrogen receptors (ER) were considered, the average staining scores in the ER negative cases were 3.2+ https://allthingsblingmiami.com/?p=21285
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Photosynthesis is the process whereby plants and many other organisms take in light, convert carbon dioxide into organic compounds and release oxygen. Oxygen is vital for life on Earth because it is needed for combustion, respiration and many other chemical reactions.
In order to keep the oxygen level in the Earth’s atmosphere stable, organisms have to balance oxygen production with oxygen consumption. Here is an example: Just like when you go for a jog, you use oxygen to burn your body’s fat stores, so too do plants use the energy in sunlight to make sugars. Then, they oxidize these sugars, and convert them back into oxygen and carbon dioxide.
Photosynthesis is incredibly important to life on Earth. There is a general consensus that the photosynthetic molecules of life arose between 3.8 to 3.5 billion years ago. However, if this process is regarded as self-sustaining, then the universe could not have had a beginning.
Theorizing about the beginning of the universe
It is well known that, as we move back in time from the present day, the universe is expanding. Initially, the expansion is very rapid (approximately 26 to 33 orders of magnitude greater than the current rate), and then it slows down (to about 6 to 7 orders of magnitude greater than the current rate). The latest findings suggest that the rate of expansion has slowed down to the current level and will continue to do so.
If the universe started from a singular point, then its observed expansion is a completely new phenomenon. The reason for the rapid expansion, and the slowing down of that expansion, is not known. These are the fundamental questions we are asking.
The first expansion
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